Disease: Fibrosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
NR3C2 P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 0.84 0.469 0.846
NPR1 P16066 natriuretic peptide receptor 1 Kinase 2.9E-04 0.608 0.654
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
GPX4 P36969 glutathione peroxidase 4 Enzyme 4.8E-05 0.516 0.808
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885